Novel therapeutics modulating CD38: an unprecedented mechanism of action involving autophagy activation against age-related diseases






ENCEFA, biopharmaceutical company steeming from the French Brain Institute (Pitié Salpêtrière Hospital, Paris), develops biologics that specifically modulate CD38 (epitope-related), a key age-related target, to fight neurodegenerative, auto-immune, and more broadly age-related diseases.







 Our approach


« Making a difference by acting very specifically on CD38,

an age-related target at the crossroad of several biological processes,

to directly regulate cell's autophagy and metabolism, while repressing inflammation: an unprecedented mechanism with the potential

to reinstate health in neurons and immune system »



Laurence BRESSAC

Co-founder, CEO

Chief executive officer, Laurence has more than 15 years of experience in project supervision, consulting, management and SME development. She made the most of her skills in international companies such as DELOITTE. She is always seeking for understanding and improvement.


Co-founder, CSO

Chief scientific officer, Damien holds a PhD in Cellular Neuroscience from the Brain and Spine Institute (ICM). Prior to join ENCEFA, Damien worked in a consulting firm specialized in life science, and then in another Biotechnology company as neuroscience project manager for experimental biology.


Co-founder, CTO

Chief technology officer, Serge is a biotech engineer. His 13 years of experience in molecule research in neuroscience firstly among Pitié Salpétrière laboratory, then ICM and then ENCEFA are key. He is at the origin of ENCEFA's discovery and has already contributed to 2 molecules in neuroscience that have been clinically tested.


Origin of our science


Institut du Cerveau et de la Moelle Epinière – ICM is a research center of international dimension that gathers patients, doctors and researchers in order to speed up the discovery of innovative therapeutic medecines against affections of the nervous system.


Our supports


ENCEFA’s team has the support of international experts, top clinicians, industrial experts with high responsibilities and successful startup managers.


Recognized institutions support Encefa:


ENCEFA's booklet
A small overview of our corporation
Brochure ENCEFA.pdf
Document Adobe Acrobat [930.1 KB]