NC-B8, our lead to protect the BRAIN


Brain penetrant, humanized, IgG4 monoclonal antibody

Intraveinous route of administration - monthly administration


Priority indication: Amyotrophic Lateral Sclerosis (ALS)

To be broaden to Parkinson's, Alzheimer's, Multiple Sclerosis



  • Strong preclinical data-package of Efficacy in two species (mice and dogs)
  • Good safety profile
  • Companion biomarkers
  • First regulatory steps