NC-B8, our lead to protect the BRAIN

Brain penetrant, humanized, IgG4 monoclonal antibody

Intraveinous route of administration - monthly administration

Priority indication: Amyotrophic Lateral Sclerosis (ALS)

To be broaden to Parkinson's, Alzheimer's, Multiple Sclerosis

Achieved:

• Strong preclinical data-package of Efficacy in two species (mice and dogs)
• Good safety profile
• Companion biomarkers
• First regulatory steps